IRX6 and TBX19

Data Source:
BioGRID (two hybrid)

		IRX6	TBX19
Description		iroquois homeobox 6	T-box transcription factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cell Development	Mesoderm Formation Cell Fate Specification Somitogenesis Heart Morphogenesis Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Pituitary Gland Development Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases			Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)
GWAS		Hypospadias ( 25108383) Lack of premeditation ( 30718321) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Visceral fat ( 22589738)
Interacting Genes		11 interacting genes: ARID5A CRX GLRX3 HOXA1 KRTAP19-7 MEOX2 NFKBID PFDN5 TBX19 TLE5 TRIB3	15 interacting genes: GCM2 HGS HOXC8 IRX6 LONRF1 NEDD9 NR5A1 PITX1 POGZ PRR35 RAB2B TBX6 TFG VENTX ZIC1
Entrez ID		79190	9095
HPRD ID		12091	05214
Ensembl ID		ENSG00000159387	ENSG00000143178
Uniprot IDs		P78412	B3KRD9 O60806
PDB IDs
Enriched GO Terms of Interacting Partners?
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