THTPA and GCDH

Data Source:
BioGRID (affinity chromatography technology)

		THTPA	GCDH
Description		thiamine triphosphatase	glutaryl-CoA dehydrogenase
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GO Annotations	Cellular Component	Cytosol	Mitochondrion Mitochondrial Matrix
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Thiamin-triphosphatase Activity	Fatty-acyl-CoA Binding Glutaryl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Thiamine Metabolic Process Dephosphorylation Thiamine Diphosphate Metabolic Process Thiamine-containing Compound Metabolic Process	Lysine Catabolic Process Tryptophan Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Fatty-acyl-CoA Biosynthetic Process
Pathways		Vitamin B1 (thiamin) metabolism	Lysine catabolism
Drugs			Flavin adenine dinucleotide S-4-Nitrobutyryl-CoA
Diseases			Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
GWAS			Blood metabolite levels ( 24816252) Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252 19862010) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		1 interacting genes: TLX3	10 interacting genes: A2M APOE CDC37 ECSIT EXOC6 MAST1 NOS3 PSEN1 PSEN2 RNF32
Entrez ID		79178	2639
HPRD ID		15505	01977
Ensembl ID		ENSG00000259431	ENSG00000105607
Uniprot IDs		G3V5Q5 Q9BU02	A0A024R7F9 Q92947
PDB IDs		3BHD 3TVL	1SIQ 1SIR 2R0M 2R0N
Enriched GO Terms of Interacting Partners?
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