GCDH and MAST1

Data Source:
BioGRID (two hybrid)

		GCDH	MAST1
Description		glutaryl-CoA dehydrogenase	microtubule associated serine/threonine kinase 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Fatty-acyl-CoA Binding Glutaryl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Lysine Catabolic Process Tryptophan Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Fatty-acyl-CoA Biosynthetic Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Lysine catabolism
Drugs		Flavin adenine dinucleotide S-4-Nitrobutyryl-CoA	Fostamatinib
Diseases		Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
GWAS		Blood metabolite levels ( 24816252) Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252 19862010) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		10 interacting genes: A2M APOE CDC37 ECSIT EXOC6 MAST1 NOS3 PSEN1 PSEN2 RNF32	40 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 UBE2D3
Entrez ID		2639	22983
HPRD ID		01977	17469
Ensembl ID		ENSG00000105607	ENSG00000105613
Uniprot IDs		A0A024R7F9 Q92947	Q9Y2H9
PDB IDs		1SIQ 1SIR 2R0M 2R0N	2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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