PLEKHF1 and KIFBP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHF1	KIFBP
Description		pleckstrin homology and FYVE domain containing 1	kinesin family binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Lysosome Lysosomal Membrane Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Cytoskeleton
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Protein Binding Kinesin Binding
	Biological Process	Apoptotic Process Endosome Organization Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial Transport Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases			Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS) Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
GWAS		Body mass index ( 26426971)
Interacting Genes		7 interacting genes: CAVIN2 CHIC2 KIFBP L3MBTL3 NPM2 TNFAIP8 TNNT1	10 interacting genes: ATXN2 CEP76 DOK2 DPEP1 HBP1 PLEKHF1 RGR TERF1 ZNF638 ZNF670
Entrez ID		79156	26128
HPRD ID		15146	13848
Ensembl ID		ENSG00000166289	ENSG00000198954
Uniprot IDs		B4DWN9 Q96S99	Q96EK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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