ASPSCR1 and NSF

Data Source:
BioGRID (pull down)

		ASPSCR1	NSF
Description		ASPSCR1 tether for SLC2A4, UBX domain containing	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Extrinsic Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Lysosomal Membrane Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft
	Molecular Function	Protein Binding	SNARE Binding Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Protein Kinase Binding PDZ Domain Binding Small GTPase Binding Ionotropic Glutamate Receptor Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Protein Modification Process Glucose Homeostasis Regulation Of Glucose Import	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Golgi Vesicle Docking
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane	COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs			1-Ethyl-Pyrrolidine-2,5-Dione
Diseases		Alveolar soft part sarcoma
GWAS		Birth weight ( 31043758) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Offspring birth weight ( 31043758)	Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (global PC1) ( 32198502) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 19915575 21812969) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Refractive error ( 32231278) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		15 interacting genes: ADAMTSL4 APP CLK2 INCA1 KRT31 KRTAP1-1 KRTAP10-8 NEDD4 NOTCH2NLA NSF PHAX TACC3 TCF4 VCP VCPKMT	28 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 MEOX2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA
Entrez ID		79058	4905
HPRD ID		06947	03380
Ensembl ID		ENSG00000169696	ENSG00000073969
Uniprot IDs		Q9BZE9	A0A384MTI6 P46459
PDB IDs		5IFS 5IFW	6KZQ
Enriched GO Terms of Interacting Partners?
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