REEP5 and PDK4

Data Source:
BioGRID (biochemical)

		REEP5	PDK4
Description		receptor accessory protein 5	pyruvate dehydrogenase kinase 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network	Mitochondrion Mitochondrial Matrix
	Molecular Function	Molecular_function Protein Binding	Protein Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding
	Biological Process	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport	Glucose Metabolic Process Protein Phosphorylation Regulation Of PH Insulin Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Cellular Ketone Metabolic Process Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Response To Starvation Regulation Of Bone Resorption Regulation Of Fatty Acid Oxidation Cellular Response To Fatty Acid Reactive Oxygen Species Metabolic Process Negative Regulation Of Anoikis
Pathways		Olfactory Signaling Pathway	Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid
Drugs			Tretinoin 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)	Refractive error ( 32231278)
Interacting Genes		13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1	4 interacting genes: DLAT PDHA1 PLEKHF2 TRIM63
Entrez ID		7905	5166
HPRD ID		15918	03957
Ensembl ID		ENSG00000129625	ENSG00000004799
Uniprot IDs		Q00765	A4D1H4 Q16654
PDB IDs			2E0A 2ZDX 2ZDY 2ZKJ 3D2R
Enriched GO Terms of Interacting Partners?
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