CACNG1 and THAP4

Data Source:
BioGRID (two hybrid)

		CACNG1	THAP4
Description		calcium voltage-gated channel auxiliary subunit gamma 1	THAP domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane T-tubule Sarcolemma L-type Voltage-gated Calcium Channel Complex	Cellular_component
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding
	Biological Process	Cardiac Conduction Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel	Tyrosine Metabolic Process Nitrate Metabolic Process
Pathways
Drugs		Ergocalciferol Enflurane Ibutilide Diltiazem Spironolactone Lercanidipine Ethanol Fluspirilene Butamben Bioallethrin
Diseases
GWAS		Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Brain structure ( 20171287) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		13 interacting genes: CPLX4 FFAR2 GAD2 GPX8 HSD17B13 LMNA MGST3 MUC1 ODF4 THAP4 TLCD4 TMEM45B VAPA	42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6
Entrez ID		786	51078
HPRD ID		00249	11630
Ensembl ID		ENSG00000108878	ENSG00000176946
Uniprot IDs		Q06432	Q8WY91
PDB IDs			3IA8
Enriched GO Terms of Interacting Partners?
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