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TUBA1A and AMHR2
Data Source:
BioGRID
(affinity chromatography technology)
TUBA1A
AMHR2
Description
tubulin alpha 1a
anti-Mullerian hormone receptor type 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Microtubule
Cytoplasmic Microtubule
Microtubule Cytoskeleton
Neuromuscular Junction
Cytoplasmic Ribonucleoprotein Granule
Myelin Sheath
Membrane Raft
Recycling Endosome
Extracellular Exosome
Plasma Membrane
Receptor Complex
Activin Receptor Complex
Molecular Function
GTPase Activity
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Protein Domain Specific Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity, Type II
Protein Binding
ATP Binding
Activin-activated Receptor Activity
Hormone Binding
Metal Ion Binding
Activin Binding
Anti-Mullerian Hormone Receptor Activity
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cytoskeleton-dependent Intracellular Transport
Regulation Of Synapse Organization
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Mullerian Duct Regression
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
Sex Differentiation
Male Gonad Development
Female Gonad Development
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Anti-Mullerian Hormone Signaling Pathway
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
Signaling by BMP
Drugs
Albendazole
Vinblastine
Mebendazole
Epothilone D
Patupilone
CYT997
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Artenimol
Phenethyl Isothiocyanate
Colchiceine
ATP
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
GWAS
Brain morphology (MOSTest) (
32665545
)
Composite immunoglobulin trait (IgG/IgM) (
28628107
)
Interacting Genes
63 interacting genes:
ANXA7
ARL3
ATXN3
B4GALT1
BTG1
C8orf33
CDKN1A
CDKN2A
CEP20
CLIP1
CNP
CPEB2
CXCR1
CYLD
DAG1
DUSP23
EGFR
EML1
GEMIN7
GRM7
GSK3B
GZMB
HDAC6
HTRA2
KEL
KPNB1
LINC01554
LRRK2
MAP2
MAP7D3
MAPK6
MAPRE1
MAX
MX1
MYC
NFATC1
NUDT3
PAFAH1B1
PLA2G7
S100A8
S100A9
SDC3
SIAH1
SMN1
SNCA
SOCS6
SOCS7
SPART
STARD13
STK11
SYK
TAOK2
TBCB
TIMM17A
TK1
TLN1
TTR
TUBB
UBE2D3
VAV1
VCL
YWHAQ
ZAP70
4 interacting genes:
AMH
BMPR1B
MAL
TGFBR1
Entrez ID
7846
269
HPRD ID
03959
02978
Ensembl ID
ENSG00000167552
ENSG00000135409
Uniprot IDs
Q71U36
Q16671
PDB IDs
5JCO
6J8F
6WSL
7C1M
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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