MOGS and VPS54

Data Source:
BioGRID (affinity chromatography technology)

		MOGS	VPS54
Description		mannosyl-oligosaccharide glucosidase	VPS54 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	GARP Complex Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	Protein Binding Syntaxin Binding
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process	Golgi To Vacuole Transport Lysosomal Transport Protein Transport Regulation Of Growth Retrograde Transport, Endosome To Golgi Homeostasis Of Number Of Cells Within A Tissue Musculoskeletal Movement Neurofilament Cytoskeleton Organization
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS			Clozapine-induced agranulocytosis ( 25187353) Diastolic blood pressure ( 30224653)
Interacting Genes		1 interacting genes: CHGB	1 interacting genes: VPS51
Entrez ID		7841	51542
HPRD ID		03214	10302
Ensembl ID		ENSG00000115275	ENSG00000143952
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	Q9P1Q0
PDB IDs
Enriched GO Terms of Interacting Partners?
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