ZKSCAN8 and MAGOH

Data Source:
BioGRID (two hybrid)

		ZKSCAN8	MAGOH
Description		zinc finger with KRAB and SCAN domains 8	mago homolog, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing
Pathways		Generic Transcription Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Mean corpuscular volume ( 27863252) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: APP FBXO7 MAGOH PRNP TCEA2 ZNF165 ZNF174 ZNF24 ZNF444 ZNF587	19 interacting genes: ALYREF CEP70 CORO1A DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B RBM8A TADA2A UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		7745	4116
HPRD ID		03760	04005
Ensembl ID		ENSG00000198315	ENSG00000162385
Uniprot IDs		A0A024RCK7 Q15776 Q59HG5	P61326
PDB IDs			1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P
Enriched GO Terms of Interacting Partners?
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