ZNF175 and LPXN

Data Source:
BioGRID (two hybrid)

		ZNF175	LPXN
Description		zinc finger protein 175	leupaxin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus	Regulation Of Transcription, DNA-templated Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: ALAS1 CDC42 KRTAP10-7 LPXN LZTR1 PSTPIP1 ZNF250 ZNF264	33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426
Entrez ID		7728	9404
HPRD ID		03088	05651
Ensembl ID		ENSG00000105497	ENSG00000110031
Uniprot IDs		Q9Y473	B7Z5P7 O60711
PDB IDs			1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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