ZNF148 and JADE1

Data Source:
BioGRID (two hybrid)

		ZNF148	JADE1
Description		zinc finger protein 148	jade family PHD finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Plasma Membrane Nuclear Speck Ciliary Basal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly	Apoptotic Process Negative Regulation Of Cell Growth Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Arterial stiffness index ( 31235810) Bone mineral density (total hip) ( 29883787)
Interacting Genes		25 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12	15 interacting genes: AKT1 CTNNB1 H3C14 H4C1 HMOX2 PFDN1 SEPTIN8 SMN1 TK1 UBE2E1 UBE2H UBE3A VHL YJU2 ZNF148
Entrez ID		7707	79960
HPRD ID		03540	10151
Ensembl ID		ENSG00000163848	ENSG00000077684
Uniprot IDs		Q9UQR1	B4E2E2 Q6IE81
PDB IDs
Enriched GO Terms of Interacting Partners?
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