ZNF148 and IFT122

Data Source:
BioGRID (two hybrid)

		ZNF148	IFT122
Description		zinc finger protein 148	intraflagellar transport 122
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus	Cytoplasm Cilium Membrane Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip Non-motile Cilium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Gamete Generation Negative Regulation Of Gene Expression Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly	Neural Tube Closure Embryonic Body Morphogenesis Embryonic Heart Tube Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Camera-type Eye Morphogenesis Limb Development Cilium Assembly Protein Localization To Cilium Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Cranioectodermal dysplasia
GWAS		Urate levels ( 31578528)	Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		25 interacting genes: CAVIN1 CEP63 CEP70 CLK1 DEUP1 EP300 GLRX3 GORASP2 JADE1 KRT31 KRT34 LNX1 LNX2 NUTM2F PFDN5 PLEKHG4 PNMA1 POU6F2 SIAH1 STAT3 TP53 TRIM10 UBC USP54 ZMYND12
Entrez ID		7707	55764
HPRD ID		03540	06922
Ensembl ID		ENSG00000163848	ENSG00000163913
Uniprot IDs		Q9UQR1	B3KUD1 B4DST2 Q9HBG6
PDB IDs
Enriched GO Terms of Interacting Partners?
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