ZNF7 and RPL7

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		ZNF7	RPL7
Description		zinc finger protein 7	ribosomal protein L7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding	DNA Binding RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Large Subunit Biogenesis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321)	Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Crohn's disease ( 22412388)
Interacting Genes		3 interacting genes: MAPK3 RPL7 TADA3	13 interacting genes: DARS1-AS1 DUX4 IL7R IPO5 NR4A1 PHC2 PPP1CC PTEN RAN SGO1 UBE2I YWHAQ ZNF7
Entrez ID		7553	6129
HPRD ID		01918	05004
Ensembl ID		ENSG00000147789	ENSG00000147604
Uniprot IDs		B4DWJ4 E9PIH3 F5H290 P17097	P18124
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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