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YWHAH and CDK16
Data Source:
BioGRID
(two hybrid)
HPRD
(in vitro, in vivo)
YWHAH
CDK16
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
cyclin dependent kinase 16
Image
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Intercalated Disc
Extracellular Exosome
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Synaptic Vesicle
Microtubule Cytoskeleton
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Neuron Projection
Molecular Function
Actin Binding
Insulin-like Growth Factor Receptor Binding
Protein Binding
Sodium Channel Regulator Activity
Enzyme Binding
Protein Domain Specific Binding
Glucocorticoid Receptor Binding
Identical Protein Binding
Ion Channel Binding
Protein Heterodimerization Activity
Protein Serine/threonine Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Regulation Of Sodium Ion Transport
Glucocorticoid Catabolic Process
Intracellular Protein Transport
Substantia Nigra Development
Glucocorticoid Receptor Signaling Pathway
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Regulation Of Synaptic Plasticity
Negative Regulation Of Dendrite Morphogenesis
Membrane Organization
Membrane Depolarization During Action Potential
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Exocytosis
Spermatogenesis
Growth Hormone Secretion
Neuron Projection Development
Regulation Of Cell Cycle
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Drugs
Phenethyl Isothiocyanate
(2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-{O-[(3R)-3,4-dihydroxybutyl]oxime}
Fostamatinib
Diseases
GWAS
Post bronchodilator FEV1 (
26634245
)
Type 2 diabetes (
30297969
)
Interacting Genes
66 interacting genes:
ABL1
ARHGEF28
BAD
BCR
BRAF
CCDC125
CDC25B
CDC25C
CDC42
CDK16
CDKN1B
CHRNA4
CREBBP
EPB41L2
EPB41L3
ESR1
ESR2
EXO1
GREM1
HSPB1
ING1
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KIF5B
KLC3
KRT18
MAP3K3
MAP3K5
MARK4
MDM4
MED1
MST1R
NCOA1
NCOA2
NCOA3
NEK1
NHSL2
NR3C1
NRIP1
PARD3
PARD6A
PARD6B
PDPK1
PRKCI
PRKN
PTH1R
RAF1
REM1
RIMS1
RIMS2
RPH3A
SAMSN1
SNCA
SRC
THRA
TLX2
TNFAIP3
TPH1
TSC1
TSC2
YWHAE
YWHAG
ZFP36
18 interacting genes:
APP
APPBP2
ATRIP
BAG6
CCND3
CDK5
CDK5R1
PJA1
PRKACA
S100A10
SEC23A
SIRPA
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZBTB14
Entrez ID
7533
5127
HPRD ID
00215
02409
Ensembl ID
ENSG00000128245
ENSG00000102225
Uniprot IDs
A0A024R1K7
Q04917
Q9H4N8
A0A024R183
A0A140VK97
Q00536
Q9BRL4
PDB IDs
2C63
2C74
3MTL
5G6V
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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