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WNT7B and CASK
Data Source:
BioGRID
(two hybrid)
WNT7B
CASK
Description
Wnt family member 7B
calcium/calmodulin dependent serine protein kinase
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Endocytic Vesicle Membrane
Extracellular Exosome
Basement Membrane
Nuclear Lamina
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Nuclear Matrix
Presynaptic Membrane
Ciliary Membrane
Molecular Function
Frizzled Binding
Cytokine Activity
Protein Binding
Receptor Ligand Activity
Guanylate Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
In Utero Embryonic Development
Metanephros Morphogenesis
Wnt Signaling Pathway
Establishment Or Maintenance Of Polarity Of Embryonic Epithelium
Forebrain Regionalization
Central Nervous System Vasculogenesis
Neuron Differentiation
Lung Development
Oxygen Homeostasis
Homeostatic Process
Cellular Metabolic Process
Cell Fate Commitment
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of JNK Cascade
Fibroblast Proliferation
Embryonic Organ Development
Synapse Organization
Canonical Wnt Signaling Pathway
Lung Morphogenesis
Lung Epithelium Development
Lobar Bronchus Development
Trachea Cartilage Morphogenesis
Developmental Growth Involved In Morphogenesis
Embryonic Placenta Morphogenesis
Chorio-allantoic Fusion
Mammary Gland Epithelium Development
Lens Fiber Cell Development
Cellular Response To Retinoic Acid
Renal Inner Medulla Development
Renal Outer Medulla Development
Outer Medullary Collecting Duct Development
Inner Medullary Collecting Duct Development
Stem Cell Proliferation
Metanephric Collecting Duct Development
Metanephric Epithelium Development
Metanephric Loop Of Henle Development
Negative Regulation Of Cell-matrix Adhesion
Protein Phosphorylation
Cell Adhesion
Neurotransmitter Secretion
Negative Regulation Of Keratinocyte Proliferation
GMP Metabolic Process
GDP Metabolic Process
Negative Regulation Of Wound Healing
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Pathways
WNT ligand biogenesis and trafficking
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)
Dopamine Neurotransmitter Release Cycle
Syndecan interactions
Nephrin family interactions
Neurexins and neuroligins
Neurexins and neuroligins
Assembly and cell surface presentation of NMDA receptors
Drugs
Formic acid
Fostamatinib
Diseases
FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS
Body mass index (
25760438
)
Central corneal thickness (
28171582
29847655
)
Corneal curvature (
25823570
)
Dupuytren's disease (
28886342
21732829
)
Heel bone mineral density (
30598549
)
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Macular thickness (
30535121
)
Optic disc size (
31809533
)
Red blood cell count (
32888494
27863252
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Type 2 diabetes (
32499647
)
Interacting Genes
5 interacting genes:
CASK
CUL3
ELOC
GPC3
PORCN
88 interacting genes:
AKAP9
APBA1
ATP2B4
BNIP3L
C20orf85
CADM1
CASKIN1
CDK9
CNTNAP2
CNTNAP4
DDX54
DLG1
DLG4
DNAJC5
DUSP3
ELL2
EPB41
EPS8
ERBIN
F11R
FCHSD2
FMR1
GCNT3
GLS2
GRIK2
GRIN2A
GTSE1
HGS
ID1
IL15RA
IL18
KCNA4
KCNJ12
KCNJ2
KCNJ4
KIF2A
KLC4
LIN7A
LIN7B
MAPRE1
MAPRE2
MARK2
MARS1
MED1
MLLT6
MLX
NDEL1
NPHS1
NRXN1
NRXN2
NRXN3
NTN4
P2RX7
PARD3B
PARD6G
PCBP2
PCM1
PKP2
PLK2
PPP4R3A
PRC1
PRKCI
PRKD2
PRKN
PRPF3
PTGS2
RAB3A
RBBP6
RBM10
RBM14
RBM5
RPA2
RPH3A
SDC1
SDC2
SDC3
SDC4
SF3B2
SH2D4A
SLAIN2
SRPK2
TANC1
TBR1
TRIM22
TSPYL2
WHRN
WNT7B
YWHAE
Entrez ID
7477
8573
HPRD ID
03573
02164
Ensembl ID
ENSG00000188064
ENSG00000147044
Uniprot IDs
A8K0G1
P56706
A0A2R8Y6F8
A0A2R8YE77
O14936
PDB IDs
1KGD
1KWA
1ZL8
3C0G
3C0H
3C0I
3MFR
3MFS
3MFT
3MFU
3TAC
6KMH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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