NELFA and NELFCD

Data Source:
HPRD (in vitro)

		NELFA	NELFCD
Description		negative elongation factor complex member A	negative elongation factor complex member C/D
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body NELF Complex	Nucleoplasm Membrane NELF Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Multicellular Organism Development Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 27863252)
Interacting Genes		12 interacting genes: APP CDK3 MLH1 NCK2 NELFB NELFCD OPRM1 PIN1 PRR22 SH3KBP1 SIAH1 SMARCD1	21 interacting genes: AAMP AR ARAF ARPC4 CACNA1A CDSN DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA NELFB PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638
Entrez ID		7469	51497
HPRD ID		12080	16096
Ensembl ID		ENSG00000185049	ENSG00000101158
Uniprot IDs		A0A0C4DFX9 Q9H3P2	H0UI80 Q8IXH7
PDB IDs		5L3X 6GML	5L3X 6GML
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?