CLIP2 and CLASP2

Data Source:
HPRD (two hybrid, in vitro)

		CLIP2	CLASP2
Description		CAP-Gly domain containing linker protein 2	cytoplasmic linker associated protein 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Associated Complex Microtubule Plus-end	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Spindle Microtubule Cytoplasmic Microtubule Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Ruffle Membrane Basal Cortex Mitotic Spindle
	Molecular Function	Microtubule Binding Microtubule Plus-end Binding	Dystroglycan Binding Protein Binding Microtubule Binding Microtubule Plus-end Binding
	Biological Process	Cytoplasmic Microtubule Organization	Microtubule Cytoskeleton Organization Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Establishment Of Mitotic Spindle Localization Positive Regulation Of Exocytosis Cell Division Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Matrix Disassembly Mitotic Spindle Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Role of ABL in ROBO-SLIT signaling RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Age at suicide ( 31476763) Autism spectrum disorders (social interaction) ( 32624584)	Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: CLASP2 DYNLL1 ITSN1 MAX	15 interacting genes: ADRB2 AKT1 CCR4 CLIP1 CLIP2 CSNK2A1 ERBB2 FEZ1 FEZ2 MAPRE1 MAPRE2 MARK3 PYGM RBFOX2 SRPK2
Entrez ID		7461	23122
HPRD ID		09140	12054
Ensembl ID		ENSG00000106665	ENSG00000163539
Uniprot IDs		A0A140VJG6 A7E2F7 Q9UDT6	E3W994 E7ERI8 O75122
PDB IDs		2CP2 2CP3	3WOY 5NR4
Enriched GO Terms of Interacting Partners?
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