EIF4H and STT3B

Data Source:
BioGRID (two hybrid)

		EIF4H	STT3B
Description		eukaryotic translation initiation factor 4H	STT3 oligosaccharyltransferase complex catalytic subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding Cadherin Binding	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translational Initiation Regulation Of Translational Initiation Viral Process Sexual Reproduction Developmental Growth Eukaryotic Translation Initiation Factor 4F Complex Assembly	Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Co-translational Protein Modification Post-translational Protein Modification
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: C11orf68 DDIT4L DLG3 FBXO17 LNX1 PICK1 SPG21	1 interacting genes: INCA1
Entrez ID		7458	201595
HPRD ID		11940	12268
Ensembl ID		ENSG00000106682	ENSG00000163527
Uniprot IDs		Q15056	Q8TCJ2
PDB IDs			6S7T
Enriched GO Terms of Interacting Partners?
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