WARS1 and MDH2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WARS1	MDH2
Description		tryptophanyl-tRNA synthetase 1	malate dehydrogenase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome
	Molecular Function	Tryptophan-tRNA Ligase Activity Protein Binding ATP Binding Kinase Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity	RNA Binding L-malate Dehydrogenase Activity Protein Self-association Malate Dehydrogenase (NADP+) Activity
	Biological Process	Angiogenesis Negative Regulation Of Protein Phosphorylation Translation TRNA Aminoacylation For Protein Translation Tryptophanyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Regulation Of Protein ADP-ribosylation Positive Regulation Of Protein-containing Complex Assembly Regulation Of Angiogenesis	Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process NADH Metabolic Process Aerobic Respiration
Pathways		Cytosolic tRNA aminoacylation	Gluconeogenesis Citric acid cycle (TCA cycle)
Drugs		Tryptophan Tryptophanyl-5'amp Tryptophanamide	NADH Citric acid Xanthinol
Diseases
GWAS			Coffee consumption ( 31959922)
Interacting Genes		10 interacting genes: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 LINC01554 MDH2 TERF1 UBC	8 interacting genes: CRYAB CS FH GOT2 HSPB1 NDUFS1 PC WARS1
Entrez ID		7453	4191
HPRD ID		01845	01099
Ensembl ID		ENSG00000140105	ENSG00000146701
Uniprot IDs		A0A024R6K8 P23381	A0A024R4K3 B3KTM1 G3XAL0 P40926
PDB IDs		1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK 5UJI 5UJJ	2DFD 4WLE 4WLF 4WLN 4WLO 4WLU 4WLV
Enriched GO Terms of Interacting Partners?
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