VPREB1 and IGHM

Data Source:
HPRD (in vitro)

		VPREB1	IGHM
Description		V-set pre-B cell surrogate light chain 1	immunoglobulin heavy constant mu
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Immunoglobulin Complex, Circulating Extracellular Exosome Pentameric IgM Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Blood Microparticle
	Molecular Function		Single-stranded DNA Binding Antigen Binding Protein Binding Phosphatidylcholine Binding Immunoglobulin Receptor Binding Peptidoglycan Binding
	Biological Process	Immunoglobulin Production Immune Response Leukocyte Migration	Adaptive Immune Response Phagocytosis, Recognition Phagocytosis, Engulfment Complement Activation, Classical Pathway Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation Leukocyte Migration
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Diastolic blood pressure ( 29208002) Periodontitis (PAL4Q3) ( 24024966) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		3 interacting genes: IGHM LGALS1 VPREB3	19 interacting genes: APP CD22 CD79A CEP72 GADD45A GSK3B HPR HSPA5 JCHAIN MAP3K20 MAPKAPK3 PTK2 SH3GL2 SMN1 TK1 UBQLN4 UFD1 VPREB1 VPREB3
Entrez ID		7441	3507
HPRD ID		05505	00912
Ensembl ID		ENSG00000169575	ENSG00000211899
Uniprot IDs		F8W8C9 P12018
PDB IDs		2H32 2H3N 3BJ9
Enriched GO Terms of Interacting Partners?
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