Description |
upstream binding transcription factor |
insulin receptor substrate 1 |
Image |
|
|
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Bipolar disorder ( 31043756)
- Body fat distribution (leg fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Diverticular disease ( 30177863)
- Mean corpuscular hemoglobin concentration ( 29403010)
- Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
|
|
Interacting Genes |
33 interacting genes:
AURKA
CCNA2
CCND1
CCNE1
CDK2
CDK4
CENPC
CHGB
CREBBP
CSNK2A1
EP300
IRS1
IRS2
LEF1
MAD1L1
MAPK1
MAPK3
MDM2
POLR1E
POLR1G
RB1
RBL2
RUNX2
SERPINH1
SMURF1
TAF1
TAF1A
TAF1B
TAF1C
TAF1D
TBP
TCOF1
ZMYM2
|
79 interacting genes:
AKT1
ALK
AP3S1
APP
ATP2A1
ATP2A2
ATP2A3
BCL2L1
BCR
CAV1
CDH1
CHUK
CRK
CSNK2A1
CSNK2B
EGFR
ERBB2
FBXO25
FBXW8
FER
FES
FYN
GHR
GRB10
GRB14
GRB2
IGF1R
IKBKB
IL4R
INSR
JAK1
JAK2
JAK3
MAPK1
MAPK3
MAPK8
MAPK9
MTOR
NCK2
NEDD4
NPM1
NTRK1
NUMB
PASK
PDPK1
PELI1
PHIP
PIK3R1
PIK3R2
PIK3R3
PLCG2
PRKCD
PRKCG
PRKCQ
PRKCZ
PTK2
PTPN1
PTPN11
PTPRC
PTPRD
PTPRF
PTPRU
RAD51
ROCK1
RPS6KB1
RPTOR
SHC1
SIK2
SOCS1
SOCS3
TRIM72
TUB
TYK2
UBC
UBTF
YWHAB
YWHAE
YWHAG
YWHAZ
|
Entrez ID |
7343 |
3667 |
HPRD ID |
02814 |
00943 |
Ensembl ID |
ENSG00000108312
|
ENSG00000169047
|
Uniprot IDs |
P17480
|
P35568
|
PDB IDs |
1K99
1L8Y
1L8Z
2HDZ
|
1IRS
1K3A
1QQG
2Z8C
5U1M
6BNT
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|