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KRTAP2-3 and ITGB4
Data Source:
BioGRID
(two hybrid)
KRTAP2-3
ITGB4
Description
keratin associated protein 2-3
integrin subunit beta 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Basement Membrane
Nucleolus
Plasma Membrane
Focal Adhesion
Integrin Complex
Basal Plasma Membrane
Cell Surface
Cell Junction
Hemidesmosome
Cell Leading Edge
Nuclear Membrane
Receptor Complex
Extracellular Exosome
Molecular Function
Protein Binding
G Protein-coupled Receptor Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor I Binding
Neuregulin Binding
Biological Process
Keratinization
Autophagy
Cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Response To Wounding
Cell Migration
Extracellular Matrix Organization
Hemidesmosome Assembly
Peripheral Nervous System Myelin Formation
Cell Adhesion Mediated By Integrin
Nail Development
Skin Morphogenesis
Filopodium Assembly
Mesodermal Cell Differentiation
Cell Motility
Trophoblast Cell Migration
Pathways
Keratinization
Keratinization
Assembly of collagen fibrils and other multimeric structures
Laminin interactions
Syndecan interactions
Type I hemidesmosome assembly
Drugs
R1295
Diseases
Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS
Interacting Genes
89 interacting genes:
ADAMTSL3
BAHD1
BCL6B
BEX2
C11orf87
CATSPER1
CHIC2
CREB5
CTSZ
CXCL16
CYSRT1
DHX57
DMRT3
FAM161A
GEMIN4
GGN
HAPLN2
HHEX
HOXA1
HOXB9
IGSF8
ITGB4
JOSD1
KLHL38
KRTAP1-1
KRTAP10-1
KRTAP12-4
KRTAP4-11
KRTAP4-12
KRTAP4-4
KRTAP5-11
KRTAP5-2
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1B
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LNX1
MCRS1
MOBP
NBPF19
NKD1
NOTCH2NLA
NPDC1
NUFIP2
OTX1
P2RY6
PHLDA1
PIGS
PRKAB2
RHBDL1
SDC3
SHFL
SPATA3
SPRED2
TFAP2D
TNP2
TRIM42
TTPA
VASN
VWC2
YY1
ZBTB24
ZDHHC1
ZIM2
ZNF165
ZNF264
ZNF440
ZNF491
ZNF524
ZNF564
ZNF575
ZNF578
ZNF581
ZNF587
ZNF672
ZNF764
ZNF786
ZNF792
59 interacting genes:
ADAMTSL4
ALOX12
APPBP2
ATXN1
CLCA1
CLCA2
COL17A1
CYSRT1
DST
ECM1
EIF6
ERBB2
ERBIN
FYN
GRB2
HOXA1
ITGA6
KPRP
KRT31
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP15-1
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP3-1
KRTAP4-2
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
MDFI
MET
MID2
MTUS2
MYF5
NBPF19
NOTCH2NLA
PLEC
PLSCR4
POU2AF1
PRKCA
PRKCD
PTK2
SDC2
SDC3
SHC1
SREBF2
TGM1
TRIP6
VIM
YES1
YWHAB
YWHAQ
Entrez ID
730755
3691
HPRD ID
00946
Ensembl ID
ENSG00000212724
ENSG00000132470
Uniprot IDs
P0C7H8
Q9BYR9
A0A024R8K7
A0A024R8N2
A0A024R8T0
B7ZLD8
P16144
PDB IDs
1QG3
2YRZ
3F7P
3F7Q
3F7R
3FQ4
3FSO
3H6A
4Q58
4WTW
4WTX
6GVK
6GVL
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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