TXN and GFER

Data Source:
HPRD (in vitro, in vivo)

		TXN	GFER
Description		thioredoxin	growth factor, augmenter of liver regeneration
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Extracellular Region Mitochondrion Mitochondrial Intermembrane Space Cytosol
	Molecular Function	RNA Binding Thioredoxin-disulfide Reductase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity Protein Homodimerization Activity Protein-disulfide Reductase Activity	Protein Binding Growth Factor Activity Protein Disulfide Oxidoreductase Activity Flavin-linked Sulfhydryl Oxidase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glycerol Ether Metabolic Process Response To Radiation Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of DNA Binding Cell Redox Homeostasis Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Protein Kinase B Signaling Response To Nitric Oxide Cellular Oxidant Detoxification Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Peptidyl-cysteine S-nitrosylation	Liver Development Signal Transduction
Pathways		Oxidative Stress Induced Senescence Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates TP53 Regulates Metabolic Genes Protein repair The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection	Mitochondrial protein import
Drugs		Phenethyl Isothiocyanate	Flavin adenine dinucleotide
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494)
Interacting Genes		38 interacting genes: ACTN1 ACTN4 ANKRD11 APEX1 CDKN1A COL1A1 COPS5 DDIT4L DNAJA1 DYNLT1 EGFR ERBB2 ERBB3 ERBB4 FST GFER GPRASP2 MAP3K5 MLH1 MRFAP1 MYD88 NCF4 NFE2 NFKB1 NIF3L1 NR3C1 NUP62 PTEN SERTAD3 SIAH1 SPG21 SRPK2 TEX13A TP53 TRAF2 TXNIP UCHL5 VIM	7 interacting genes: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN
Entrez ID		7295	2671
HPRD ID		01761	02954
Ensembl ID		ENSG00000136810	ENSG00000127554
Uniprot IDs		H9ZYJ2 P10599	P55789
PDB IDs		1AIU 1AUC 1CQG 1CQH 1ERT 1ERU 1ERV 1ERW 1M7T 1MDI 1MDJ 1MDK 1TRS 1TRU 1TRV 1TRW 1W1C 1W1E 2HSH 2HXK 2IFQ 2IIY 3E3E 3KD0 3M9J 3M9K 3QFA 3QFB 3TRX 4LL1 4LL4 4OO4 4OO5 4POK 4POL 4POM 4PUF 4TRX 5DQY	3MBG 3O55 3TK0 3U2L 3U2M 3U5S 4LDK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?