TNFRSF4 and H6PD

Data Source:
HPRD (in vivo)

		TNFRSF4	H6PD
Description		TNF receptor superfamily member 4	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Mitochondrion Endoplasmic Reticulum Lumen
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding	Glucose-6-phosphate Dehydrogenase Activity 6-phosphogluconolactonase Activity Carbohydrate Binding Glucose 1-dehydrogenase [NAD(P)] Activity NADP Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell	Glucose Metabolic Process Pentose-phosphate Shunt, Oxidative Branch Response To Alcohol Regulation Of Cortisol Biosynthetic Process
Pathways		TNFs bind their physiological receptors
Drugs			NADH
Diseases			Cortisone reductase deficiency (CRD)
GWAS		Inflammatory bowel disease ( 23128233)	Blood protein levels ( 30072576 29875488) Height ( 25282103 23563607 31562340) Hip circumference ( 28552196)
Interacting Genes		10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5
Entrez ID		7293	9563
HPRD ID		02636	00681
Ensembl ID		ENSG00000186827	ENSG00000049239
Uniprot IDs		P43489	O95479
PDB IDs		1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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