C6 and OGA

Data Source:
HPRD (two hybrid)

		C6	OGA
Description		complement C6	O-GlcNAcase
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Exosome	Nucleus Cytosol Membrane
	Molecular Function	Protein Binding	Hyalurononglucosaminidase Activity Beta-N-acetylglucosaminidase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase Activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase Activity
	Biological Process	In Utero Embryonic Development Complement Activation Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation Innate Immune Response	N-acetylglucosamine Metabolic Process Protein O-linked Glycosylation Glycoprotein Catabolic Process Protein Deglycosylation Glycoprotein Metabolic Process Viral Process
Pathways		Terminal pathway of complement Regulation of Complement cascade
Drugs			Streptozocin
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 28240269) Refractive error ( 32231278) Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		4 interacting genes: C5 F2 OGA SART3	10 interacting genes: A2M C6 CDC37 CSNK2B DHX9 GSK3B MAST1 OGT PSEN2 RNF32
Entrez ID		729	10724
HPRD ID		01956	04949
Ensembl ID		ENSG00000039537	ENSG00000198408
Uniprot IDs		P13671	O60502
PDB IDs		3T5O 4A5W 4E0S 6H03 6H04	2YDQ 5M7R 5M7S 5M7T 5M7U 5TKE 5UHK 5UHL 5UHO 5UHP 5UN8 5UN9 5VVO 5VVT 5VVU 5VVV 5VVX 6HKI 6PM9
Enriched GO Terms of Interacting Partners?
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