TUFT1 and RAB27B

Data Source:
HPRD (in vivo)

		TUFT1	RAB27B
Description		tuftelin 1	RAB27B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Intracellular Anatomical Structure Cytoplasm	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Tooth Enamel	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Bone Mineralization Intracellular Signal Transduction Odontogenesis	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways			Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		11 interacting genes: ABCD3 BIRC2 CCDC33 CEP76 KAT5 LMO2 LMO3 NME7 TFIP11 TRIM27 ZYX	11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		7286	5874
HPRD ID		02516	04846
Ensembl ID		ENSG00000143367	ENSG00000041353
Uniprot IDs		B7Z4Y1 Q9NNX1	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?
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