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TUBG1 and CTRL
Data Source:
BioGRID
(biochemical)
TUBG1
CTRL
Description
tubulin gamma 1
chymotrypsin like
Image
No pdb structure
GO Annotations
Cellular Component
Condensed Nuclear Chromosome
Gamma-tubulin Complex
Nucleus
Cytoplasm
Centrosome
Spindle
Polar Microtubule
Cytosol
Microtubule
Recycling Endosome
Mitotic Spindle Microtubule
Extracellular Space
Molecular Function
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Identical Protein Binding
Serine-type Endopeptidase Activity
Protein Binding
Serine-type Peptidase Activity
Biological Process
Mitotic Sister Chromatid Segregation
G2/M Transition Of Mitotic Cell Cycle
Meiotic Spindle Organization
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule Nucleation
Mitotic Spindle Organization
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cytoplasmic Microtubule Organization
Ciliary Basal Body-plasma Membrane Docking
Proteolysis
Protein Catabolic Process
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Vinblastine
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
28 interacting genes:
APP
BRCA1
CENPJ
CNTN2
CUL4A
DDX41
IKBKG
KIF14
KRT18
KRT19
MARK4
NAPG
NDE1
PCNT
PIK3R1
PLK1
PXN
RACGAP1
RACK1
RASSF1
RNF19A
RPGR
SPATC1
TUBA1B
TUBA3C
TUBB4B
TUBGCP3
TUBGCP4
4 interacting genes:
CLDN5
FAM209A
FATE1
SERPINA3
Entrez ID
7283
1506
HPRD ID
01853
00344
Ensembl ID
ENSG00000131462
ENSG00000141086
Uniprot IDs
P23258
A0A024R6Z5
P40313
PDB IDs
1Z5V
1Z5W
3CB2
6V5V
6V6S
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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