TTF1 and AMPH

Data Source:
BioGRID (two hybrid)

		TTF1	AMPH
Description		transcription termination factor 1	amphiphysin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Cytosol Plasma Membrane Synaptic Vesicle Actin Cytoskeleton Synaptic Vesicle Membrane Leading Edge Membrane
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	Protein Binding Phospholipid Binding
	Biological Process	DNA-templated Transcription, Termination Termination Of RNA Polymerase I Transcription Negative Regulation Of DNA Replication Cellular Protein Metabolic Process	Endocytosis Chemical Synaptic Transmission Synaptic Vesicle Endocytosis Membrane Organization
Pathways		ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression Surfactant metabolism RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Transcription Termination	Clathrin-mediated endocytosis
Drugs
Diseases		Benign hereditary chorea
GWAS			Ankylosing spondylitis ( 30946743) Bitter non-alcoholic beverage consumption ( 31046077) Cerebral microbleeds ( 31209788) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		6 interacting genes: BAZ2A CAVIN1 KAT2B NFATC3 SMAD1 SMAD7	27 interacting genes: AP2A2 ARL16 BIN1 CABIN1 CDK1 CDK5 CDK5R1 CLTC DEUP1 DNM1 DNM2 DYRK1A ITSN2 KHDRBS1 MAPK6 MAPT NECAP1 PLD2 PPP3CA PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		7270	273
HPRD ID		02866	02687
Ensembl ID		ENSG00000125482	ENSG00000078053
Uniprot IDs		A0A024R8C1 A0A087WY09 Q15361	P49418
PDB IDs			1KY7 1UTC 3SOG 4ATM 5M5S 5M61
Enriched GO Terms of Interacting Partners?
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