CCT3 and MIPOL1

Data Source:
BioGRID (two hybrid)

		CCT3	MIPOL1
Description		chaperonin containing TCP1 subunit 3	mirror-image polydactyly 1
Image			No pdb structure
GO Annotations	Cellular Component	Zona Pellucida Receptor Complex Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Cell Body Extracellular Exosome	Nucleus
	Molecular Function	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Pore Complex Assembly Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester Artenimol
Diseases
GWAS		Basophil count ( 32888494) Glycated hemoglobin levels ( 24647736) Household income (MTAG) ( 31844048) Mean corpuscular hemoglobin concentration ( 20139978) Mean corpuscular volume ( 29403010) Red blood cell count ( 29403010) Red cell distribution width ( 32888494) Subcutaneous adipose tissue ( 22589738)	Eosinophil percentage of white cells ( 32888494) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Longitudinal alcohol consumption ( 26081443) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Red blood cell count ( 32888494) Tonsillectomy ( 27182965 28928442)
Interacting Genes		24 interacting genes: BUD31 DEPDC5 EIF2B2 ERBB2 FANCA GEMIN4 HNRNPA0 HSPA8 LINC01554 LNX2 MAPK6 MIPOL1 PAFAH1B2 PDCL POLR1C PTEN RAF1 SH3BP4 SUMO2 UBE2Z VAV2 VHL XRCC6 ZNRD2	73 interacting genes: ANKRD23 ARNT2 ATP5PO BEX2 BYSL C1orf109 C1orf35 C2CD6 CCDC120 CCDC146 CCDC33 CCT3 CDC37 CDK18 CKS1B DAXX DGCR6 EAF1 EIF4E2 ENKD1 EXOC8 FAM124B FAM161A FAM161B FAM90A1 FBF1 FMNL2 GADD45GIP1 GEM HAUS1 KDF1 KIF9 LAGE3 LENG1 MAGEA6 MBD3 MCM7 MFAP1 MOS MYLIP NEBL NTAQ1 PAX6 PBX4 PKN1 PPP1R13B PRDM16 PRPF31 RBM41 RCOR3 REL RIIAD1 RNF6 RTP5 SCNM1 SMARCE1 SNAP91 SNTG2 SRPK2 SSX3 STMN3 TBC1D7 TCHP TSEN15 TSGA10IP TTC12 TXN2 UBE2I UBE2K USH1C UTP25 ZGPAT ZNF688
Entrez ID		7203	145282
HPRD ID		08969	06029
Ensembl ID		ENSG00000163468	ENSG00000151338
Uniprot IDs		B3KX11 P49368 Q59H77	A8K735 G5EA54 Q4G0U7 Q8TD10
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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