TRH and IQCB1

Data Source:
HPRD (in vivo, in vitro)

		TRH	IQCB1
Description		thyrotropin releasing hormone	IQ motif containing B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Plasma Membrane Secretory Granule	Photoreceptor Outer Segment Nucleoplasm Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Photoreceptor Connecting Cilium Intercellular Bridge Extracellular Exosome Mitotic Spindle
	Molecular Function	Protein Binding Thyrotropin-releasing Hormone Activity	Protein Binding Calmodulin Binding Enzyme Binding
	Biological Process	Response To Hypoxia Histamine Metabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Cold Response To Glucose Hormone-mediated Signaling Pathway Negative Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Insulin Secretion Eating Behavior Response To Ethanol Response To Corticosterone Negative Regulation Of Feeding Behavior	Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome
GWAS		Alzheimer's disease ( 30636644) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hemoglobin levels ( 32327693) Multiple sclerosis ( 31604244 24076602) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
Interacting Genes		5 interacting genes: ARRB2 CPE KCNIP4 LCN2 TRHR	12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32
Entrez ID		7200	9657
HPRD ID		08944	11049
Ensembl ID		ENSG00000170893	ENSG00000173226
Uniprot IDs		P20396	Q15051
PDB IDs
Enriched GO Terms of Interacting Partners?
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