TPM3 and TFPT

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TPM3	TFPT
Description		tropomyosin 3	TCF3 fusion partner
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Ino80 Complex
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	DNA Binding Protein Binding
	Biological Process	Muscle Contraction Actin Filament Organization Muscle Filament Sliding	DNA Repair DNA Recombination Protein Deubiquitination Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway
Pathways		Striated Muscle Contraction Smooth Muscle Contraction	UCH proteinases DNA Damage Recognition in GG-NER
Drugs		Phenethyl Isothiocyanate
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010 32888494) Mean reticulocyte volume ( 32888494) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Obesity-related traits ( 23251661)
Interacting Genes		59 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CAVIN3 CCDC102B CCDC146 CCHCR1 CHRM3 CNN1 DVL2 FAM9C FBXO5 FGA HDDC3 HOOK2 HSF2 HSF4 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 MAST2 NEK2 NOD2 NUP54 ODAD1 OIP5 PBX3 PHLDB3 PSMC5 S100A2 S100A4 SMAD3 SNAPIN SUMO4 SYCE1 TAB2 TFPT THAP1 THAP7 TLK1 TMOD1 TMOD2 TNNI1 TNNT1 TPM4 TRAP1 TRIM27 TRIP6 TSKS VPS52 WASH3P WASHC1	32 interacting genes: APP C19orf25 C4orf46 CCDC57 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL ENTR1 HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 PIN1 PSMB1 RALBP1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM2 TPM3 TRAF1
Entrez ID		7170	29844
HPRD ID		01840	10266
Ensembl ID		ENSG00000143549	ENSG00000105619
Uniprot IDs		A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753	A0A024R4Q5 P0C1Z6
PDB IDs		6OTN
Enriched GO Terms of Interacting Partners?
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