CLEC3B and PLAT

Data Source:
HPRD (in vitro)

		CLEC3B	PLAT
Description		C-type lectin domain family 3 member B	plasminogen activator, tissue type
Image
GO Annotations	Cellular Component	Granular Component Extracellular Region Extracellular Space Cytoplasm Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Cytoplasm Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Heparin Binding Carbohydrate Binding Kringle Domain Binding	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Phosphoprotein Binding
	Biological Process	Ossification Platelet Degranulation Positive Regulation Of Plasminogen Activation Bone Mineralization Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus	Cellular Protein Modification Process Proteolysis Blood Coagulation Smooth Muscle Cell Migration Plasminogen Activation Fibrinolysis Negative Regulation Of Proteolysis Platelet-derived Growth Factor Receptor Signaling Pathway
Pathways		Platelet degranulation	Signaling by PDGF Dissolution of Fibrin Clot
Drugs		Tenecteplase Lanoteplase Copper	Aminocaproic acid Iloprost Human C1-esterase inhibitor 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Dexibuprofen Conestat alfa
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576)	Blood protein levels ( 30072576) Plasma plasminogen activator levels ( 24578379) Systemic lupus erythematosus ( 28714469)
Interacting Genes		12 interacting genes: ANXA7 APP CDKN1A GADD45A GSK3B HGF PLAT PLG RPS6KA6 RPS6KB1 SH3GL2 TK1	27 interacting genes: ANXA2 APP CALR CKAP4 CLEC3B F10 FGA FN1 GRIN1 HMGB1 KRT8 LAMA1 LAMA3 LRP1 LRP1B MAPK1 MAPK3 MTDH PDGFC PLAU PLG SERPINA5 SERPINE1 SERPING1 SERPINI1 SPARC VDAC1
Entrez ID		7123	5327
HPRD ID		01759	01419
Ensembl ID		ENSG00000163815	ENSG00000104368
Uniprot IDs		E9PHK0 P05452	B4DN26 P00750
PDB IDs		1HTN 1RJH 1TN3 3L9J	1A5H 1BDA 1PK2 1PML 1RTF 1TPG 1TPK 1TPM 1TPN 5BRR 5ZLZ
Enriched GO Terms of Interacting Partners?
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