KLF10 and PIGC

Data Source:
BioGRID (two hybrid)

		KLF10	PIGC
Description		Kruppel like factor 10	phosphatidylinositol glycan anchor biosynthesis class C
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Circadian Rhythm Negative Regulation Of Cell Population Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Population Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Peptide	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane
Pathways			Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 23770605) IgA nephropathy ( 26028593) Neurofibrillary tangles ( 31497858) Urate levels ( 31578528)	Daytime sleep phenotypes ( 27126917) Hemoglobin levels ( 32327693) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		17 interacting genes: BOP1 CDK2 CDK6 CRIP2 FBXW7 KAT2B LENG1 PIGC RPL14 SF3B3 SIAH1 SIN3A SNHG29 SP1 TNS1 TULP3 ZNF512B	4 interacting genes: DPM2 KLF10 PIGQ ZHX1
Entrez ID		7071	5279
HPRD ID		03527	03433
Ensembl ID		ENSG00000155090	ENSG00000135845
Uniprot IDs		Q13118	Q92535
PDB IDs		2EPA
Enriched GO Terms of Interacting Partners?
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