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TH and DAAM2
Data Source:
BioGRID
(two hybrid)
TH
DAAM2
Description
tyrosine hydroxylase
dishevelled associated activator of morphogenesis 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Smooth Endoplasmic Reticulum
Cytosol
Synaptic Vesicle
Cytoplasmic Side Of Plasma Membrane
Axon
Dendrite
Cytoplasmic Vesicle
Melanosome Membrane
Neuron Projection
Terminal Bouton
Perikaryon
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Tyrosine 3-monooxygenase Activity
Protein Binding
Ferrous Iron Binding
Ferric Iron Binding
Amino Acid Binding
Oxygen Binding
Enzyme Binding
Protein Domain Specific Binding
Tetrahydrobiopterin Binding
Dopamine Binding
Actin Binding
Biological Process
Response To Hypoxia
Synaptic Transmission, Dopaminergic
Response To Amphetamine
Heart Morphogenesis
Dopamine Biosynthetic Process From Tyrosine
Fatty Acid Metabolic Process
Sphingolipid Metabolic Process
Heart Development
Visual Perception
Sensory Perception Of Sound
Learning
Memory
Mating Behavior
Locomotory Behavior
Regulation Of Heart Contraction
Response To Water Deprivation
Response To Light Stimulus
Response To Herbicide
Response To Salt Stress
Anatomical Structure Morphogenesis
Animal Organ Morphogenesis
Response To Zinc Ion
Multicellular Organism Aging
Response To Activity
Aminergic Neurotransmitter Loading Into Synaptic Vesicle
Glycoside Metabolic Process
Phthalate Metabolic Process
Cerebral Cortex Development
Response To Nutrient Levels
Response To Estradiol
Response To Lipopolysaccharide
Isoquinoline Alkaloid Metabolic Process
Social Behavior
Cellular Response To Drug
Response To Isolation Stress
Response To Immobilization Stress
Neurotransmitter Biosynthetic Process
Terpene Metabolic Process
Dopamine Biosynthetic Process
Epinephrine Biosynthetic Process
Norepinephrine Biosynthetic Process
Catecholamine Biosynthetic Process
Eye Photoreceptor Cell Development
Circadian Sleep/wake Cycle
Eating Behavior
Response To Peptide Hormone
Pigmentation
Response To Ethanol
Response To Ether
Response To Pyrethroid
Embryonic Camera-type Eye Morphogenesis
Response To Corticosterone
Response To Electrical Stimulus
Phytoalexin Metabolic Process
Cellular Response To Manganese Ion
Cellular Response To Alkaloid
Cellular Response To Nicotine
Cellular Response To Glucose Stimulus
Cellular Response To Growth Factor Stimulus
Hyaloid Vascular Plexus Regression
Wnt Signaling Pathway
Dorsal Spinal Cord Development
Actin Cytoskeleton Organization
Negative Regulation Of Oligodendrocyte Differentiation
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Non-canonical Wnt Signaling Pathway
Pathways
Catecholamine biosynthesis
Drugs
Phenylalanine
Tyrosine
Sapropterin
Metyrosine
3-Tyrosine
L-erythro-7,8-dihydrobiopterin
Diseases
Primary torsion dystonia (PTD)
GWAS
Celiac disease (
23936387
)
Height (
31562340
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Prostate cancer (
19767753
)
Prostate cancer (early onset) (
24740154
)
Prostate cancer (SNP x SNP interaction) (
22219177
)
Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) (
29310926
)
Type 1 diabetes in high risk HLA genotype individuals (time to event) (
29310926
)
Type 2 diabetes (
31324766
25102180
)
Brain morphology (MOSTest) (
32665545
)
Heel bone mineral density (
30598549
)
Height (
31562340
)
Hypospadias (
25108383
)
Intraocular pressure (
29785010
)
Pulmonary function (
20010834
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
23 interacting genes:
CAMK2G
CDK11B
CRABP1
CSNK2A1
DAAM2
HNRNPK
MAPK1
MAPK3
MAPKAPK2
MDFI
NFIC
PIAS2
PRKACA
PUF60
RBMY1A1
RPS6KA5
SNCA
TSPYL4
TYSND1
UMAD1
YWHAB
YWHAZ
ZNF569
14 interacting genes:
EHHADH
EXOSC5
HGS
KCNIP1
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
MDFI
RBMY1A1
RBMY1F
REL
TH
Entrez ID
7054
23500
HPRD ID
01865
09434
Ensembl ID
ENSG00000180176
ENSG00000146122
Uniprot IDs
P07101
P78428
A0A0J9YYF7
Q86T65
PDB IDs
2XSN
4J6S
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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