DYNLT1 and CRHBP

Data Source:
BioGRID (genetic interference)

		DYNLT1	CRHBP
Description		dynein light chain Tctex-type 1	corticotropin releasing hormone binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Extracellular Region Extracellular Space Nucleus Secondary Lysosome Multivesicular Body Endoplasmic Reticulum Golgi Apparatus Microtubule Secretory Granule Dendrite Dense Core Granule Varicosity Perikaryon Axon Terminus
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Protein Binding Peptide Binding Corticotropin-releasing Hormone Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Synaptic Transmission, Dopaminergic Inflammatory Response Signal Transduction Female Pregnancy Learning Or Memory Hormone-mediated Signaling Pathway Cellular Response To Drug Cellular Response To Potassium Ion Regulated Exocytosis Behavioral Response To Ethanol Regulation Of Corticotropin Secretion Negative Regulation Of Corticotropin Secretion Cellular Response To Calcium Ion Cellular Response To Cocaine Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Estrogen Stimulus Cellular Response To Estradiol Stimulus Regulation Of Cellular Response To Stress Cellular Response To Gonadotropin-releasing Hormone Negative Regulation Of Corticotropin-releasing Hormone Receptor Activity Regulation Of NMDA Receptor Activity
Pathways		Neutrophil degranulation	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Chronotype ( 30696823) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	2 interacting genes: ERRFI1 UCN
Entrez ID		6993	1393
HPRD ID		15987	08348
Ensembl ID		ENSG00000146425	ENSG00000145708
Uniprot IDs		P63172	P24387
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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