TCTA and SLC35A1

Data Source:
BioGRID (two hybrid)

		TCTA	SLC35A1
Description		T cell leukemia translocation altered	solute carrier family 35 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane
	Molecular Function	Molecular_function Protein Binding	CMP-N-acetylneuraminate Transmembrane Transporter Activity UDP-galactose Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Negative Regulation Of Osteoclast Differentiation Osteoclast Fusion	Carbohydrate Metabolic Process Cellular Protein Modification Process Carbohydrate Transport CMP-N-acetylneuraminate Transmembrane Transport UDP-galactose Transmembrane Transport
Pathways			Sialic acid metabolism Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Transport of nucleotide sugars
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908) Metabolite levels ( 23823483) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Bone mineral density (hip) ( 30172743) Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: ADRB2 ATXN1 BMP10 CMTM7 SLC35A1 SMAD4 YIPF6	36 interacting genes: AQP6 ARL13B ASGR2 ASZ1 BCL2L13 CD53 CERS4 CPLX4 EBAG9 ERGIC3 F11R F2RL1 FAM209A FNDC9 FXYD3 GPX8 KIR3DL3 LHFPL5 LMNA MCFD2 MGST3 MRPS18B PIK3IP1 PLPP4 PSCA RELL2 SAR1A SDC3 SLC1A1 SLC34A2 SSMEM1 SYT2 TCTA TMEM139 TMPRSS2 TMX2
Entrez ID		6988	10559
HPRD ID		15977	09290
Ensembl ID		ENSG00000145022	ENSG00000164414
Uniprot IDs		P57738	P78382
PDB IDs
Enriched GO Terms of Interacting Partners?
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