TCP10L3 and CEP43

Data Source:
BioGRID (two hybrid)

		TCP10L3	CEP43
Description		t-complex 10 like 3, pseudogene	centrosomal protein 43
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Centrosome Centriole Cytosol Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: APP FBXO7 PARD6A PARD6B UBC	5 interacting genes: CEP19 NAGK PPP2R1B S100A6 VASP
Entrez ID		6953	11116
HPRD ID		01752	10392
Ensembl ID		ENSG00000203690	ENSG00000213066
Uniprot IDs			A0A087WV25 B4DH64 O95684
PDB IDs			2D68
Enriched GO Terms of Interacting Partners?
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