Description |
transcription factor 4 |
twist family bHLH transcription factor 2 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Ability to confide in someone ( 29970889)
- Adult body size ( 32376654)
- Adventurousness ( 30643258)
- Alcohol consumption ( 31358974)
- Alcohol consumption (drinks per week) ( 30643258)
- anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
- Automobile speeding propensity ( 30643258)
- Bitter alcoholic beverage consumption ( 31046077)
- Brain morphology (MOSTest) ( 32665545)
- Broad depression or schizophrenia ( 30626913)
- Chin dimples ( 27182965)
- Chronotype ( 30696823)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Corneal endothelial cell density ( 30894546)
- Corneal endothelial cell shape (percentage of hexagonally shaped cells) ( 30894546)
- Corneal hysteresis ( 30894546)
- Corneal resistance factor ( 31246245 30894546)
- Depression ( 29700475)
- Diabetic retinopathy ( 21441570)
- Diastolic blood pressure ( 30224653)
- Experiencing mood swings ( 29500382)
- Feeling fed-up ( 29500382)
- Feeling lonely ( 29500382)
- Feeling worry ( 29500382)
- Fuchs's corneal dystrophy ( 28358029 20825314)
- General factor of neuroticism ( 30867560)
- General risk tolerance (MTAG) ( 30643258)
- Hand grip strength ( 29691431 29313844)
- Heart rate response to exercise ( 29769521)
- Heel bone mineral density ( 30598549)
- Household income (MTAG) ( 31844048)
- Intraocular pressure ( 29617998 31798171 29235454)
- Irritable mood ( 29500382)
- Loneliness ( 31518406 29970889)
- Loneliness (MTAG) ( 29970889)
- Male-pattern baldness ( 28196072)
- Mental health study participation (completed survey) ( 31263887)
- Mood instability ( 31168069)
- Morning person ( 30696823)
- Neurociticism ( 29500382)
- Number of sexual partners ( 30643258)
- Obesity (early onset extreme) ( 23563609)
- Post bronchodilator FEV1/FVC ratio ( 26634245)
- Prostate cancer ( 29892016)
- Prostate cancer (advanced) ( 29892016)
- Pulse pressure ( 30578418)
- Refractive error ( 32231278)
- Regular attendance at a gym or sports club ( 29970889)
- Regular attendance at a religious group ( 29970889)
- Risk-taking tendency (4-domain principal component model) ( 30643258)
- Schizophrenia ( 28991256 25056061 21926974 19571808 19571811 29483656 22688191 30285260 23974872 23894747)
- Sclerosing cholangitis and ulcerative colitis (combined) ( 22821403)
- Self-rated health ( 27864402)
- Self-reported risk-taking behaviour ( 30271922)
- Sleep duration (short sleep) ( 30846698)
- Social science traits (pleiotropy) (HIPO component 1) ( 30289880)
- Systolic blood pressure ( 30578418)
- Tea consumption ( 31046077)
- Type 2 diabetes ( 30297969)
- Urinary albumin excretion ( 30220432)
- Urinary albumin-to-creatinine ratio ( 31630189 31511532)
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Interacting Genes |
226 interacting genes:
ALKBH4
AQP1
AR
ARHGEF1
ARHGEF5
ARL16
ARMC7
ASAP3
ASCL1
ASCL3
ASCL4
ASPSCR1
ATG9A
ATOH7
ATP11B
ATP6V1B2
BACH1
BANF2
BCAS2
BCL2L15
BCL2L2
C1orf109
C1orf50
C1orf56
CABP5
CALM1
CALM2
CALM3
CBFA2T2
CCNH
CDC37
CDC73
CDKN1A
CDKN2C
CFAP77
CHAF1A
CHCHD2
CHIC2
CKS1B
CLCNKA
COA5
CPNE2
CTBP1
CTNNB1
DAXX
DDX6
DEF6
DGCR6
DMRT3
DNTT
DUSP23
DUSP29
EFHC1
EIF4E2
EIF4EBP1
EP300
EPB41L3
EPHB6
EXOC8
EXOSC1
FAH
FAM110A
FAM124B
FAM74A4
FERD3L
FIGLA
FLAD1
FLNA
FRS3
GEM
GLRX3
GNG10
GOLGA8EP
GOLGA8F
GORASP2
GTF3C5
GUCD1
HAND2
HAT1
HBP1
HSPB7
ID1
ID2
ID3
ID4
INS
JUN
JUP
KCTD14
KLC3
KLHL32
KLHL38
LASP1
LENG1
LGALS14
LHX4
LMO1
LMO4
LNPEP
LYL1
MAD2L2
MAGOHB
MAPKBP1
MARF1
MATN3
MEMO1
MLLT6
MORN4
MRFAP1L1
MRPL10
MSC
MSGN1
MSRB3
MVP
MYO15B
MYO5B
MYOD1
NCK2
NDOR1
NECTIN2
NEK6
NEK8
NEU4
NEUROD1
NEUROD4
NEUROG1
NEUROG3
NFAM1
NFKBID
NHLH2
NME7
NMUR2
NOL9
NOXA1
NR2C2AP
NR4A1
NUDT10
NUDT22
NXPE2
NXT2
OLFM3
ORC4
OSGIN1
OTUD4
PARP1
PATE1
PBLD
PIN1
PLEKHN1
POLR1A
POLR1C
PPIA
PPIL1
PPP1R18
PRKAA2
PRKAB2
PRKN
PSMA1
PSMG2
PTF1A
PTGER3
RAB41
RABIF
RAD51D
RECK
RELA
REXO1L6P
RNF6
RSPH14
RUNX1T1
SCOC
SCX
SDCBP
SEC14L4
SGF29
SHFL
SIGLEC6
SLC39A13
SLC4A1AP
SMCP
SMG9
SMOC1
SPATC1L
SPG21
SPO11
SRSF2
STAMBPL1
STK16
STX11
SZT2
TAL1
TAL2
TAPBPL
TCEA2
TCF23
TCF24
TCF3
TCL1A
TLE1
TLE5
TMEM213
TP53
TRAPPC2L
TRIM68
TRIML2
TSPOAP1
TSSC4
TSSK3
TSTD2
TTF2
TWIST1
TWIST2
TXNL4B
UBASH3B
UBE2I
UTP23
VPS28
XRCC5
XRCC6
ZDHHC24
ZMYND10
ZNF124
ZNF205-AS1
ZNF417
ZNF587
ZNF688
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9 interacting genes:
CRK
FERD3L
GLIS2
MEF2C
PLCG2
SREBF1
TCF12
TCF3
TCF4
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Entrez ID |
6925 |
117581 |
HPRD ID |
03780 |
09616 |
Ensembl ID |
ENSG00000196628
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ENSG00000233608
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Uniprot IDs |
A0A024R2C0
A0A1B0GW91
A0A1B0GWD5
B3KVA4
E9PH57
H3BPJ7
H3BTP3
P15884
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A1MB48
Q8WVJ9
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PDB IDs |
2KWF
6OD3
6OD4
6OD5
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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