TAZ and CCDC88C

Data Source:
BioGRID (affinity chromatography technology)

		TAZ	CCDC88C
Description		tafazzin	coiled-coil domain containing 88C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Cytoplasm Centrosome Cell Junction
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity Frizzled Binding Protein Binding Microtubule Binding PDZ Domain Binding Identical Protein Binding Protein Self-association Dynein Light Intermediate Chain Binding
	Biological Process	Muscle Contraction Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Cardiac Muscle Tissue Development Cardiac Muscle Contraction	Regulation Of Protein Phosphorylation Apical Constriction Small GTPase Mediated Signal Transduction Cytoskeleton-dependent Intracellular Transport Stress-activated Protein Kinase Signaling Cascade Cytoplasmic Microtubule Organization Protein Destabilization Non-canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL	Negative regulation of TCF-dependent signaling by DVL-interacting proteins
Drugs
Diseases		3-Methylglutaconic aciduria (MGCA) Barth syndrome (BTHS) Dilated cardiomyopathy (DCM)
GWAS			Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683 23535729) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Daytime sleep phenotypes ( 27126917) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: BTRC CHGB CSNK1E GSK3B LATS1 LATS2 RUNX1 SLC9A3R2 YWHAE	6 interacting genes: APP DVL1 FBXO7 GNAI3 ITSN2 MAPK8
Entrez ID		6901	440193
HPRD ID		02316	19136
Ensembl ID		ENSG00000102125	ENSG00000015133
Uniprot IDs		A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635	B4DZB8 Q9P219
PDB IDs
Enriched GO Terms of Interacting Partners?
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