TAF9 and TAF6L

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		TAF9	TAF6L
Description		TATA-box binding protein associated factor 9	TATA-box binding protein associated factor 6 like
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex Pre-snoRNP Complex MLL1 Complex	Histone Deacetylase Complex SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex SLIK (SAGA-like) Complex Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding P53 Binding DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Activating Transcription Factor Binding Protein Heterodimerization Activity ATPase Binding C2H2 Zinc Finger Domain Binding	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	Box C/D SnoRNP Assembly Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process SnRNA Transcription By RNA Polymerase II Negative Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Positive Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Somatic Stem Cell Population Maintenance
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HATs acetylate histones
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		57 interacting genes: AHR ANK2 APP CEBPB CIITA COIL DRAP1 EEF1A1 ELF3 FBL FBLN1 FEZ1 GALNT6 GLI1 GLI2 GLI3 GTF2B H3-4 HCFC1 HNF4A HSF1 KLF6 KMT2A KPNA1 KPNA6 LAMTOR5 MAGEC2 MYC NCOA2 NCOR1 NDRG1 NFATC2 NR1D2 NUFIP1 PJA1 RBM48 RELA RNF138 RPS14 RPS24 RUVBL1 RUVBL2 SF3B3 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF6L TAF7 TAF8 TBCA TP53 UBA1	7 interacting genes: CREBBP H3-4 MYOG PFDN5 STX11 TAF9 TAF9B
Entrez ID		6880	10629
HPRD ID		15983	04253
Ensembl ID		ENSG00000273841	ENSG00000162227
Uniprot IDs		Q16594	A0A024R5A7 A8K0D4 Q9Y6J9
PDB IDs		6F3T 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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