SYPL1 and PPIF

Data Source:
BioGRID (two hybrid)

		SYPL1	PPIF
Description		synaptophysin like 1	peptidylprolyl isomerase F
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Secretory Granule Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Melanosome Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Syntaxin-1 Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding
	Biological Process	Chemical Synaptic Transmission	Protein Peptidyl-prolyl Isomerization Response To Ischemia Protein Folding Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Cyclosporine Proline Triglyme Coumarin 120
Diseases
GWAS			Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Triglyceride levels ( 32203549)
Interacting Genes		10 interacting genes: ARFGAP3 CIB3 LMNA PBX3 PPIF RBFA SDCBP TARS2 TEX44 VAMP2	19 interacting genes: ABI2 AGTRAP ARFIP2 BANP CIDEB CMTM5 FAM25A FAM25C FAM25G FKBP7 MAGEA11 MUC1 PRB3 SERPINB5 SLC25A4 SYP SYPL1 VDAC1 YIF1A
Entrez ID		6856	10105
HPRD ID		15459	06839
Ensembl ID		ENSG00000008282	ENSG00000108179
Uniprot IDs		A4D0R1 Q16563	A0A024QZS4 P30405
PDB IDs			2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1 6Y3E 6YBM
Enriched GO Terms of Interacting Partners?
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