SVIL and MRTFB

Data Source:
BioGRID (two hybrid)

		SVIL	MRTFB
Description		supervillin	myocardin related transcription factor B
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere	Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Transcription Coactivator Activity Protein Binding Cadherin Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping	Muscle Organ Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)
Interacting Genes		35 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	7 interacting genes: KDM3A MRTFA NCOA3 SMAD1 SMAD7 SRF SVIL
Entrez ID		6840	57496
HPRD ID		04992	17577
Ensembl ID		ENSG00000197321	ENSG00000186260
Uniprot IDs		A0A6I8PIX7 O95425 Q569J5	Q9ULH7
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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