SURF2 and NPTN

Data Source:
BioGRID (two hybrid)

		SURF2	NPTN
Description		surfeit 2	neuroplastin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Plasma Membrane Nuclear Speck	Immunological Synapse Plasma Membrane Cell Surface Axon Dendrite Presynaptic Membrane Inhibitory Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Active Zone Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Molecular_function	Type 1 Fibroblast Growth Factor Receptor Binding Protein Binding Ion Channel Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Biological_process	Negative Regulation Of Cytokine Production Positive Regulation Of Protein Phosphorylation Cellular Calcium Ion Homeostasis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Cytosolic Calcium Ion Concentration Axon Guidance Visual Learning Positive Regulation Of Neuron Projection Development Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Long-term Synaptic Potentiation Positive Regulation Of ERK1 And ERK2 Cascade Dendrite Self-avoidance Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Receptor Localization To Synapse Positive Regulation Of Cellular Protein Localization Excitatory Synapse Assembly
Pathways			GABA receptor activation
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Malaria ( 31844061)	Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Tourette syndrome ( 30818990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APP B4GALT3 NPTN PLAUR PRNP ZNF331	3 interacting genes: AGTR1 SURF2 UBC
Entrez ID		6835	27020
HPRD ID		15948	18033
Ensembl ID		ENSG00000148291	ENSG00000156642
Uniprot IDs		Q15527	Q9Y639
PDB IDs			6A69
Enriched GO Terms of Interacting Partners?
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