ZFP36L1 and PRKCH

Data Source:
BioGRID (biochemical)

		ZFP36L1	PRKCH
Description		ZFP36 ring finger protein like 1	protein kinase C eta
Image
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Metal Ion Binding 14-3-3 Protein Binding	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Enzyme Binding Metal Ion Binding
	Biological Process	MAPK Cascade Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Vasculogenesis Proepicardium Development MRNA Processing Apoptotic Process Heart Development Cell Population Proliferation Response To Wounding Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Phosphatidylinositol 3-kinase Signaling Neural Tube Development Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay Regulation Of MRNA 3'-end Processing Cellular Response To Insulin Stimulus T Cell Differentiation In Thymus Multicellular Organism Growth P38MAPK Cascade Regulation Of MRNA Stability Protein Kinase B Signaling Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Regulation Of Keratinocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Monocyte Differentiation Regulation Of Myoblast Differentiation Mesendoderm Development MRNA Transport Chorio-allantoic Fusion 3'-UTR-mediated MRNA Destabilization ERK1 And ERK2 Cascade Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Hypoxia Cellular Response To Salt Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Stem Cell Proliferation Cellular Response To Raffinose Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intracellular MRNA Localization	Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Platelet Activation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly
Pathways		Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	Effects of PIP2 hydrolysis G alpha (z) signalling events
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 31959851) Blond vs. brown/black hair color ( 30531825) Celiac disease ( 22057235 20190752 25920553) Crohn's disease ( 21102463) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Fibrinogen levels ( 28107422 26561523) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Microalbuminuria ( 31511532) Multiple sclerosis ( 24076602 21833088) Nonsyndromic cleft lip ( 31609978) Prostate cancer ( 23535732) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 30423114 22446963 24390342) Word reading ( 23738518) Yeast infection ( 28928442)
Interacting Genes		9 interacting genes: ACD AKT1 MAPK14 MAPKAPK2 PAFAH1B2 POT1 TERF1 TINF2 YWHAB	12 interacting genes: BANP CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS
Entrez ID		677	5583
HPRD ID		03041	05669
Ensembl ID		ENSG00000185650	ENSG00000027075
Uniprot IDs		A0A024R658 B3KNA8 Q07352	P24723
PDB IDs		1W0V 1W0W	2FK9 3TXO
Enriched GO Terms of Interacting Partners?
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