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SP3 and GABPA
Data Source:
BioGRID
(affinity chromatography technology, pull down)
HPRD
(in vivo)
SP3
GABPA
Description
Sp3 transcription factor
GA binding protein transcription factor subunit alpha
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
PML Body
Transcription Repressor Complex
Protein-DNA Complex
Chromatin
Nucleus
Nucleoplasm
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Activating Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ossification
Natural Killer Cell Differentiation
Trophectodermal Cell Differentiation
Liver Development
Embryonic Placenta Development
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
B Cell Differentiation
T Cell Differentiation
Megakaryocyte Differentiation
Monocyte Differentiation
Lung Development
Granulocyte Differentiation
Enucleate Erythrocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Camera-type Eye Morphogenesis
Embryonic Skeletal System Development
Embryonic Process Involved In Female Pregnancy
Definitive Hemopoiesis
Negative Regulation Of Transcription By RNA Polymerase II
Blastocyst Formation
Regulation Of Transcription By RNA Polymerase II
Mitochondrion Organization
Positive Regulation Of Gene Expression
Cell Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Dopamine
Pathways
SUMOylation of transcription factors
Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS
End-stage renal disease in Type 1 diabetics (
24029427
)
Lung cancer (
28604730
)
Male-pattern baldness (
27182965
)
Mosquito bite size (
28199695
)
Otitis media (chronic/recurrent) (
23974705
)
QT interval (
24952745
29874175
)
Sensation seeking (
30718321
)
Gout (normal type) (
32238385
)
Nicotine dependence symptom count (
25555482
)
Interacting Genes
29 interacting genes:
AKT1
CIB3
E2F1
EP300
ESR1
GABPA
GCH1
GRIN1
HDAC1
HDAC2
HLTF
LIN54
NKX3-1
PHF21A
PIAS1
POGZ
RB1
RBBP4
RPS20
SNRPB
SP1
SPANXN2
STK19
SUMO1
TP53
TP73
UBE2I
VEGFA
ZBTB7A
13 interacting genes:
APP
ATF1
CREBBP
EP300
GABPB1
GABPB2
HCFC1
MED1
PINX1
SP1
SP3
STK16
ZC2HC1B
Entrez ID
6670
2551
HPRD ID
03483
11793
Ensembl ID
ENSG00000172845
ENSG00000154727
Uniprot IDs
B7ZLN9
Q02447
Q59FX5
Q86TP0
A8IE48
Q06546
Q8IYS3
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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