Description |
Sp1 transcription factor |
POU class 2 homeobox 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Asthma ( 31959851 31619474)
- Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
- Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
- Diastolic blood pressure ( 30224653)
- Liver enzyme levels ( 18940312)
- Pre-treatment viral load in HIV-1 infection ( 31219150)
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Interacting Genes |
146 interacting genes:
AATF
AHR
AKT1
AR
ARHGAP21
ARNT
ATF7IP
ATF7IP2
BCL11B
BCL6
BCOR
BRCA1
CASP3
CASP6
CASP7
CBX5
CCNA1
CCNA2
CCND1
CD2
CDK1
CDK2
CEBPB
CSNK2A1
CTCFL
CTNNB1
DDX5
DROSHA
E2F1
E2F2
E2F3
EGR1
ELF1
EP300
ESR1
ESR2
ESRRA
ESRRB
ESRRG
ETS1
GABPA
GATA1
GATA3
GATA4
HBZ
HCFC1
HDAC1
HDAC2
HIF1A
HINT1
HLTF
HMGA1
HNF4A
HOXC11
HSPA8
HTT
IL1B
JUN
KIF1A
KLF10
KLF4
KLF6
LDB1
LMO2
MAPK1
MAPK3
MAPK8
MBD1
MEF2C
MEF2D
MIER1
MIS18BP1
MSX1
MTREX
MYC
MYCN
MYOD1
MYOG
NAP1L1
NCOR1
NCOR2
NEPRO
NFKB1
NFKB2
NFYA
NFYB
NFYC
NKX3-1
NOS3
NPM1
NR2F1
NR5A1
NUP62
OGT
PARP1
PER3
PML
POGZ
POU2F1
PPIG
PPP1R13L
PRKCZ
PRKDC
PSIP1
PSMC5
PURA
RARA
RB1
RBBP4
RBL1
REL
RELA
RNF4
RORA
RXRA
SENP6
SF3A1
SHC1
SMAD2
SMAD3
SMAD4
SMARCC1
SMARCC2
SOX10
SOX8
SP3
SP4
SREBF1
SREBF2
SRF
SUB1
SUMO2
TAF4
TAL1
TBP
TLX3
TP53
TP73
TPI1
USP39
VEGFA
VHL
YY1
ZBTB16
ZBTB2
ZBTB7A
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68 interacting genes:
APP
AR
ARPC3
ARRB1
BARD1
BRCA1
CEBPE
CREB1
CREM
ESR1
FDXR
HCFC1
HIVEP1
HMGA1
HMGB2
HNF1A
HOXB13
HOXC9
IRF9
LIFR
MLLT10
MNAT1
MSX1
NCOR2
NFYA
NPAT
NR3C1
PARP1
PBX1
PGR
PKNOX1
PLK3
POGZ
POU2AF1
POU6F2
PPIP5K2
PRKACA
PRKDC
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RARA
RELA
RXRA
SNAPC4
SNIP1
SNX24
SOX2
SP1
SP4
STAT5A
STAT5B
STOX1
TBP
THRA
TLE4
TLE5
TLX2
TNF
TXNRD1
UBE2I
VDR
XRCC6
ZC3H10
ZFHX3
ZMYM6
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Entrez ID |
6667 |
5451 |
HPRD ID |
01796 |
01250 |
Ensembl ID |
ENSG00000185591
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ENSG00000143190
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Uniprot IDs |
P08047
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A0A024R8Y2
P14859
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PDB IDs |
1SP1
1SP2
1VA1
1VA2
1VA3
6PV0
6PV1
6PV2
6PV3
6UCO
6UCP
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1CQT
1E3O
1GT0
1HF0
1O4X
1OCT
1POG
1POU
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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