SNCG and GRK6

Data Source:
BioGRID (enzymatic study)

		SNCG	GRK6
Description		synuclein gamma	G protein-coupled receptor kinase 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Spindle Neuronal Cell Body Axon Terminus Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Membrane
	Molecular Function	Protein Binding Cuprous Ion Binding	G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity
	Biological Process	Chemical Synaptic Transmission Adult Locomotory Behavior Protein Secretion Regulation Of Dopamine Secretion Regulation Of Neurotransmitter Secretion Synaptic Vesicle Endocytosis Synapse Organization Regulation Of Neuron Death	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway
Pathways			G alpha (s) signalling events
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Cardiac troponin-I levels ( 31014085) Chronic kidney disease ( 20383146) Extremely high intelligence ( 29520040) Glycine levels ( 30837465) Intelligence (MTAG) ( 29326435) Metabolite levels ( 22916037) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: ADRB2 BUB1B GRK1 GRK5 GRK6 MAPK1 MAPK3 MAPK8 PCBP1 POT1 TERF1 TERF2IP	19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R
Entrez ID		6623	2870
HPRD ID		04297	02925
Ensembl ID		ENSG00000173267	ENSG00000198055
Uniprot IDs		F8W754 O76070 Q6FHG5	B3KPS5 P43250
PDB IDs			2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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