BNIP1 and HSD17B11

Data Source:
BioGRID (two hybrid)

		BNIP1	HSD17B11
Description		BCL2 interacting protein 1	hydroxysteroid 17-beta dehydrogenase 11
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane COPI-coated Vesicle Integral Component Of Endoplasmic Reticulum Membrane SNARE Complex Mitochondrial Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	SNAP Receptor Activity Protein Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Apoptotic Process Endoplasmic Reticulum Organization Response To Activity Viral Process Endoplasmic Reticulum Membrane Fusion Response To Starvation Negative Regulation Of Apoptotic Process Response To Oxygen-glucose Deprivation Execution Phase Of Apoptosis	Estrogen Biosynthetic Process Androgen Catabolic Process
Pathways		COPI-dependent Golgi-to-ER retrograde traffic	Estrogen biosynthesis
Drugs			Aetiocholanolone
Diseases
GWAS		Glaucoma (primary open-angle) ( 29891935) Infantile hypertrophic pyloric stenosis ( 22306654) PR interval ( 30679814 30046033 32439900) Pulse pressure ( 30578418)	Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		25 interacting genes: APP BCL2 BCL2L1 CYB561 ELOVL4 ERBB2 FAM174A GPR35 HSD17B11 JAGN1 MARCHF5 NAPA NCBP1 PTGER4 RETREG3 SCN3B SLC7A14 STOM STX18 STX1A TM4SF19 TMEM31 TMX2 TSHR VMA21	59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6
Entrez ID		662	51170
HPRD ID		04480	10881
Ensembl ID		ENSG00000113734	ENSG00000198189
Uniprot IDs		Q12981	Q8NBQ5
PDB IDs			1YB1
Enriched GO Terms of Interacting Partners?
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