SLC18A1 and VAMP5

Data Source:
BioGRID (two hybrid)

		SLC18A1	VAMP5
Description		solute carrier family 18 member A1	vesicle associated membrane protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Terminal Bouton Clathrin-sculpted Monoamine Transport Vesicle Membrane	Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Serotonin:sodium Symporter Activity Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding
	Biological Process	Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Xenobiotic Transport Serotonin Uptake Transmembrane Transport	Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters
Drugs		Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cholesterol ( 31902109) Coronary artery disease ( 30104761) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertriglyceridemia ( 23505323) Major depressive disorder (broad) ( 20038947) Metabolic syndrome ( 30382898 31589552) Pulse pressure ( 27841878) Susceptibility to persistent hepatitis B virus infection ( 27244555) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Triglycerides ( 18193046 24886709)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Platelet distribution width ( 32888494) Prostate cancer ( 21743467) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		60 interacting genes: AGTRAP ANKRD46 APOL2 BRICD5 C2CD2L CCL4 CCL4L2 CNIH1 COL4A5 CTSA CXCL16 CYB561D2 FAM3C FCER1G FXYD3 GIMAP1 GJB2 GPR151 LAT MALL MFSD6 MGAM MIP MS4A1 MS4A13 NEU1 NRM OLFM4 ORMDL1 PEX16 PLP1 PLP2 PMP22 PNLIPRP1 RPRM SLC30A2 SLC30A8 SLC35B4 SLC35G1 SLC38A7 SLC39A2 SMCO4 SMIM1 STX2 STX8 TFRC TMEM120B TMEM128 TMEM14A TMEM14B TMEM203 TMEM218 TMEM239 TMEM42 TMEM60 TMEM65 TMEM86A VAMP5 YIPF4 YIPF6	59 interacting genes: ABHD16A AQP6 ASGR2 ATP6AP2 BIK CD53 CLDN5 CLDN7 COMT CPLX4 CYB5R3 ELOVL4 FAM209A FNDC9 GJA8 GORAB GPR152 GPX8 GRAMD2B HIBADH IL3RA JAGN1 KIR2DL3 KIR3DL3 KLRC1 LMNA LRRC25 MDC1 MUC1 NCAPH2 PANX1 PLAC8 PVR RETREG3 SAR1A SLC14A2 SLC18A1 SNAP29 SPINT1 STX16 STX1A STX1B STX2 STX4 STX5 STX8 TAS2R5 TM4SF18 TMCO5A TMEM106C TMEM139 TMEM14B TMEM31 TMEM45B TMEM52B TMEM86B TMPRSS2 TMX2 VSIG4
Entrez ID		6570	10791
HPRD ID		01897	09513
Ensembl ID		ENSG00000036565	ENSG00000168899
Uniprot IDs		P54219 Q96GL6	O95183 Q6FG93
PDB IDs
Enriched GO Terms of Interacting Partners?
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